Endocrine Abstracts

Biochemists have defined a probably complete catalogue of proteins involved in insulin secretion. Similarly, over the last two decades, biochemists and physiologists have defined the physical characteristics of different types of ion channels that underlie normal pancreatic beta cell physiology. What is missing is information describing the ‘wheres and whens’: where are these proteins (i.e. not just for example on the surface of a cell, but how are the single protein...